Drug or tool, design or serendipity?

New Platforms For Drug Screening And Toxicology: Necessity Or Need?

The liver is the largest internal organ in the human body that is responsible for more than 500 vital functions, including biosynthesis of major plasma proteins, immunity against infectious pathogens, balancing energy metabolism and xenobiotics biotransformation (1). One of the main functions of the liver is an important role in drug metabolism (2). Since developing new drug compounds into mark...

Anticancer Drug Discovery — From Serendipity to Rational Design

Cancer is nowadays used as a generic term describing a group of about 120 different diseases, which can affect any part of the body and defined as the state characterized by the uncontrolled growth and invasion of normal tissues and spread of cells [1]. According to WHO reports cancer is a leading cause of premature death worldwide, accounting for 7.6 million deaths (around 13% of all deaths) o...

Serendipity or Preparedness? Quantifying Creativity in Scientific Enterprise

Human creativity is the ultimate driving force behind all of scientific progress. The building blocks of innovations are often embodied in existing knowledge, yet it is creativity that blends seemingly disparate concepts, ideas and theories. Existing studies attempt to understand this phenomenon by investigating reference relationships of scientific publications. Unfortunately, an article’s ref...

Interatrial shunt-associated migraine: serendipity, empiricism, hope, or hype?

Ethnography in design: tool-kit or analytic science?

The role of ethnography in system development is discussed through the selective application of an ethnographic easy-to-use toolkit, Contextual Design, by a computer firm in the initial stages of the development of a health care system.